EPMD, Eclipse Prism Medical Devices
BioMIS™

Biologically Relevant Multispectral Imaging System

Beyond seeing anatomy. Toward understanding biology.

From controlled illumination and spectral detection to computation - turning optical responses into biological information for clinical innovators, OEM teams, researchers, and strategic partners.

The future of surgery will not be defined by seeing more alone, but by understanding more - and turning that understanding into better-informed decisions.

Dr. Rohan Nagare
What Multispectral Imaging can reveal

A broader view of biology

By measuring how tissue absorbs, scatters, and returns light across channels, Multispectral Imaging can surface information that is difficult to distinguish from conventional broadband images alone. Explore the light-tissue science.

Conventional white light

Conventional white-light view of oral tissue vasculature
Appearance-first broadband imaging of the same anatomy.

BioMIS™ visualization

Two-tone BioMIS™ visualization highlighting superficial and deeper vascular structures
Spectrally informed contrast for vascular and microvascular detail.
What BioMIS™ can open

Spectral channel signals into biological insight

BioMIS™ turns wavelength-resolved measurements into parameters that help partners explore tissue function, composition, and change.

  • Hemodynamics

    Vascular structures and blood-related optical contrast.

  • Oxygenation

    Relative differences linked to oxy- and deoxyhemoglobin spectra.

  • Perfusion

    Spatial and temporal patterns in tissue blood distribution.

  • Tissue composition

    Contributions from lipids, water, and other chromophores.

  • Structural information

    Architecture and microstructure via wavelength-dependent scattering.

  • Temporal change

    How spectral signals evolve with functional dynamics over time.

How signals evolve

Seeing change over time

Beyond a static frame, Multispectral Imaging can track how oxygenation and hemodynamics shift across a dynamic acquisition.

Oxygenation

Animated multispectral visualization of apparent tissue oxygen saturation over time
Apparent StO2-related contrast across a dynamic acquisition.

Hemodynamics

Animated multispectral visualization of absolute hemoglobin response during a cuff challenge
Absolute hemoglobin-related response across baseline, cuff-on, and cuff-off.

Illustrative / investigational visualizations for technology discussion. Not a claim of a cleared clinical indication or diagnostic performance.

Where BioMIS™ can apply

Surgical Imaging Applications

One platform. Across the surgical spectrum.

Surgical imaging applications: open surgery, rigid endoscopy, flexible endoscopy, surgical microscopy, and image-guided surgery on one BioMIS™ platform direction
The EPMD Multispectral Imaging technology

EPMD's Integrated Technology Stack at BioMIS™

We approach multispectral imaging as an integrated technology stack - not as a light source, camera, algorithm, or software component in isolation.

BioMIS™ brings together controlled illumination, optical detection, acquisition, signal processing, algorithms, and visualization as interconnected layers of one system. Every layer shapes what can be extracted from tissue - and our objective is the complete pathway from controlled light to information.

New to Multispectral Imaging? Read What Is Multispectral Imaging? and The Science of Multispectral Imaging.

EPMD's integrated technology stack at BioMIS™

EPMD integrated BioMIS™ technology stack: illuminate, detect, acquire, process, analyze, and visualize across physical measurement and computational information layers
Collaborate with EPMD

Build with us. At the level you need.

BioMIS™ sits on 30+ years of medical-device experience across illumination, detection, imaging, electronics, software, and manufacturing. Not every partner needs the entire platform - we engage where your technology, application, or stage of development needs us most.

How we can collaborate

  • Technology & modules

    Develop or integrate optical, illumination, imaging, sensing, or electronic modules around a defined requirement.

  • Algorithms & visualization

    Build processing pipelines, derived imaging parameters, application-specific visualization, and AI exploration where it adds value.

  • Systems, OEM & manufacturing

    Co-develop complete imaging systems, integrate into an OEM platform, or take a design from prototype through production.

  • Clinical & advisory

    Collaborate on feasibility, translational studies, and validation - or engage EPMD for architecture, engineering, and regulatory planning.

From a single module to a complete medical imaging system - we engage where we add the most value.

Next step

Explore the EPMD BioMIS™ ecosystem

EPMD is developing multiple technologies within the Multispectral Imaging ecosystem at different stages of readiness. Talk with BioMIS™ leadership about pathways that match your application and stage of development.

To know more about BioMIS™, contact directly:

Dr. Rohan Nagare

Program Director, BioMIS™

IIT | MS | PhD - Light & Health

Former Senior Scientist, Mount Sinai | NIH Grant Awardee

rohan.nagare@epmdgroup.com